NO-donating aspirin inhibits intestinal carcinogenesis in Min (APCMin/+) mice

A Randomized Trial of Aspirin to Prevent Colorectal Adenomas

John A. Baron, Bernard F. Cole, Robert S. Sandler et al. · New England Journal of Medicine · 2003 · 1.4K citations · Full text

Medicine, Pharmacology, Pharmacotherapy +9

A Randomized Trial of Aspirin to Prevent Colorectal Adenomas in Patients with Previous Colorectal Cancer

Robert S. Sandler, Susan Halabi, John A. Baron et al. · New England Journal of Medicine · 2003 · 1.2K citations

Medicine, Oncology, Pharmacology +15

The cyclooxygenase-2 inhibitor celecoxib is a potent preventive and therapeutic agent in the min mouse model of adenomatous polyposis.

Russell F. Jacoby, Karen Seibert, Carolyn E. Cole et al. · PubMed · 2000 · 483 citations

Medicine, Pharmacology, Pharmacotherapy +14

Gastrointestinal safety of NO-aspirin (NCX-4016) in healthy human volunteers: A proof of concept endoscopic study

Stefano Fiorucci, Luca Santucci, Paolo Gresele et al. · Gastroenterology · 2003 · 222 citations · Full text

Medicine, Clinical Sciences, Pharmacology +8

Nitric oxide-releasing nonsteroidal anti-inflammatory drugs (NSAIDs) alter the kinetics of human colon cancer cell lines more effectively than traditional NSAIDs: implications for colon cancer chemoprevention.

Janne Williams, Simona Borgo, Imtiaj Hasan et al. · PubMed · 2001 · 137 citations

Medicine, Oncology, Pharmacology +11