Russell F. Jacoby

The cyclooxygenase-2 inhibitor celecoxib is a potent preventive and therapeutic agent in the min mouse model of adenomatous polyposis.

Russell F. Jacoby, Karen Seibert, Carolyn E. Cole et al. · PubMed · 2000 · 483 citations

Chemoprevention Strategy, Therapeutic Target Cox-2, Apoptosis +20

MLH3: a DNA mismatch repair gene associated with mammalian microsatellite instability

Steven M. Lipkin, Victoria Wang, Russell F. Jacoby et al. · Nature Genetics · 2000 · 327 citations

Genome Instability, Genetic Disorder, Genetics +5

Chemoprevention of spontaneous intestinal adenomas in the Apc Min mouse model by the nonsteroidal anti-inflammatory drug piroxicam.

Russell F. Jacoby, D. J. Marshall, Michael A. Newton et al. · PubMed · 1996 · 295 citations

Inflammation, Tumor Biology, Oncology +15

Intestinal neoplasia in the ApcMin mouse: independence from the microbial and natural killer (beige locus) status.

William F. Dove, Linda Clipson, Karen A. Gould et al. · PubMed · 1997 · 159 citations

Dysbiosis, Mucosal Immunology, Pathogenesis +15

Chemopreventive efficacy of combined piroxicam and difluoromethylornithine treatment of Apc mutant Min mouse adenomas, and selective toxicity against Apc mutant embryos.

Russell F. Jacoby, Carolyn E. Cole, Kendra D. Tutsch et al. · PubMed · 2000 · 152 citations

Tumor Biology, Chemoprevention Strategy, Selective Cox-2 Inhibition +14