Allelic variation in theDR subregion of the canine major histocompatibility complex

DNA sequencing with chain-terminating inhibitors

Frederick Sanger, S. Nicklen, Alan Coulson · Proceedings of the National Academy of Sciences · 1977 · 69.3K citations · Full text

Life Sciences, Microbiology, Molecular Biology +10

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

John M. Chirgwin, Alan Przybyla, Raymond J. MacDonald et al. · Biochemistry · 1979 · 22.2K citations

Life Sciences, Biochemistry, Molecular Biology +9

Enzymatic Amplification of β-Globin Genomic Sequences and Restriction Site Analysis for Diagnosis of Sickle Cell Anemia

Randall K. Saiki, Stephen J. Scharf, Fred Faloona et al. · Science · 1985 · 9K citations

Medicine, Genetics, Molecular Genetics +17

Natural history of the major histo-compatibility complex

Gene · 1987 · 1.3K citations

Life Sciences, Biology, Genetics +10

A hypothetical model of the foreign antigen binding site of Class II histocompatibility molecules

Jerry H. Brown, Theodore S. Jardetzky, Mark A. Saper et al. · Nature · 1988 · 1.2K citations

Life Sciences, Immunology, Molecular Biology +14