Tanshinone I selectively suppresses pro-inflammatory genes expression in activated microglia and prevents nigrostriatal dopaminergic neurodegeneration in a mouse model of Parkinson׳s disease

In vivo imaging of microglial activation with [11C](R)-PK11195 PET in idiopathic Parkinson's disease

Alexander Gerhard, Nicola Pavese, Gary Hotton et al. · Neurobiology of Disease · 2005 · 1.2K citations · Full text

Medicine, Neurology, Neuroscience +15

Blockade of Microglial Activation Is Neuroprotective in the 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine Mouse Model of Parkinson Disease

Du Chu Wu, Vernice Jackson‐Lewis, Miquel Vila et al. · Journal of Neuroscience · 2002 · 1.2K citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Minocycline prevents nigrostriatal dopaminergic neurodegeneration in the MPTP model of Parkinson's disease

Yansheng Du, Zhizhong Ma, Suizhen Lin et al. · Proceedings of the National Academy of Sciences · 2001 · 786 citations · Full text

Life Sciences, Neuroscience, Pharmacology +17

Minocycline attenuates lipopolysaccharide (LPS)-induced neuroinflammation, sickness behavior, and anhedonia

Christopher J. Henry, Yan Huang, Angela Wynne et al. · Journal of Neuroinflammation · 2008 · 660 citations · Full text

Medicine, Neuroscience, Pharmacology +17

Role of neuronal nitric oxide in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced dopaminergic neurotoxicity.

Serge Przedborski, Vernice Jackson‐Lewis, R Yokoyama et al. · Proceedings of the National Academy of Sciences · 1996 · 629 citations

Medicine, Neuroscience, Pharmacology +17