Concepedia

Polyol pathway and protein kinase C activity of rat Schwannoma cells

Hideki Kamiya, Jiro Nakamura, Yoji Hamada, Eitaro Nakashima, Keiko Naruse, Koichi Kato, Yutaka Yasuda, Nigishi Hotta

Diabetes/Metabolism Research and Reviews · 2002 · 30 citations · 36 references

Abstract

These results suggest that PKC, especially PKC-alpha activity, is decreased in Schwann cells exposed to high glucose and that this deficit is mediated through polyol pathway hyperactivity.

References

36

A new collection method for the evaluation of nasal mucus proteins

L. Ruocco, Fattori, Romanelli et al. · Clinical & Experimental Allergy · 1998 · 1.3K citations

The Natural History of Diabetic Autonomic Neuropathy

D J Ewing, I. W. Campbell, B. F. Clarke · QJM · 1980 · 746 citations

Hypertension, Heart Failure, Social Sciences +19

Preferential elevation of protein kinase C isoform beta II and diacylglycerol levels in the aorta and heart of diabetic rats: differential reversibility to glycemic control by islet cell transplantation.

Toyoshi Inoguchi, Ruggero Battan, Eugene S. Handler et al. · Proceedings of the National Academy of Sciences · 1992 · 738 citations · Full text

Pancreas Transplantation, Insulin Signaling, Oxidative Stress +21

Characterization of protein kinase C beta isoform activation on the gene expression of transforming growth factor-beta, extracellular matrix components, and prostanoids in the glomeruli of diabetic rats.

Daisuke Koya, M.R. Jirousek, Y W Lin et al. · Journal of Clinical Investigation · 1997 · 537 citations · Full text

Growth Factor-beta, Extracellular Matrix Components, Insulin Signaling +21

Targeted overexpression of protein kinase C β2 isoform in myocardium causes cardiomyopathy

Hisao Wakasaki, Daisuke Koya, Frederick J. Schoen et al. · Proceedings of the National Academy of Sciences · 1997 · 381 citations · Full text