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Multiple FAS1 domains and the RGD motif of TGFBI act cooperatively to bind αvβ3 integrin, leading to anti-angiogenic and anti-tumor effects

AngiogenesisSignaling PathwayTgfbi ActReceptor Tyrosine KinaseVascular BiologyRgd MotifMultiple Fas1 DomainsRadiation OncologyMedicineCell BiologyCell SignalingTumor BiologyCancer GrowthMolecular Signaling