Impact of clarithromycin resistance on the effectiveness of a regimen for <i>Helicobacter pylori</i>: a prospective study of 1‐week lansoprazole, amoxycillin and clarithromycin in active peptic ulcer

Abstract

Clarithromycin resistance significatively impairs the effectiveness of the combination of lansoprazole, amoxycillin, and clarithromycin. The 80% efficacy goal will be difficult to reach in areas with high (>10%) primary clarithromyicin resistance, if currently recommended proton pump inhibitor-triple therapies are used.