Concepedia

Regulation of Osteoclast Differentiation and Function by Phosphate: Potential Role of Osteoclasts in the Skeletal Abnormalities in Hypophosphatemic Conditions

Tetsuyuki Hayashibara, Toru Hiraga, Atsushi Sugita, Liyang Wang, Kenji Hata, Takashi Ooshima, Toshiyuki Yoneda

Journal of Bone and Mineral Research · 2007 · 49 citations · 27 references

DOI

Abstract

Our results suggest that Pi controls the differentiation and function of osteoclasts. These actions of Pi on osteoclasts may be associated with the pathogenesis of the skeletal abnormalities in hypophosphatemic disorders.

References

27

Targeted ablation of Fgf23 demonstrates an essential physiological role of FGF23 in phosphate and vitamin D metabolism

Takashi Shimada, Makoto Kakitani, Y. Yamazaki et al. · Journal of Clinical Investigation · 2004 · 1.4K citations · Full text

Targeted ablation of Fgf23 demonstrates an essential physiological role of FGF23 in phosphate and vitamin D metabolism

Takashi Shimada, Makoto Kakitani, Y. Yamazaki et al. · Journal of Clinical Investigation · 2004 · 1.3K citations · Full text

Pathogenic role of Fgf23 in <i>Hyp</i> mice

Shiguang Liu, Jianping Zhou, Wen Tang et al. · American Journal of Physiology-Endocrinology and Metabolism · 2006 · 486 citations

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Dietary and Serum Phosphorus Regulate Fibroblast Growth Factor 23 Expression and 1,25-Dihydroxyvitamin D Metabolism in Mice

Farzana Perwad, Nasreen Azam, Martin Y. H. Zhang et al. · Endocrinology · 2005 · 425 citations · Full text

, , +20

Dietary Phosphorus Regulates Serum Fibroblast Growth Factor-23 Concentrations in Healthy Men

Diana M. Antoniucci, Takeyoshi Yamashita, Anthony A. Portale · The Journal of Clinical Endocrinology & Metabolism · 2006 · 421 citations