Hypocholesteremic Effect of  -Diethylaminoethyl Diphenylpropylacetate Hydrochloride (SKF No. 525-A) in the Dog

Abstract

Summaryβ-Diethylaminoethyl diphenylpropylacetate hydrochloride (SKF No. 525-A) reduced significantly plasma total cholesterol and aortic cholesterol in dogs. Chronic daily administration of the SKF No. 525-A to dogs for 5 months resulted in marked fatty infiltration of the liver, which was rapidly reversible upon withdrawal of the compound.