Concepedia

CSF-1 blockade impairs breast cancer osteoclastogenic potential in co-culture systems

Chiara Liverani, Laura Mercatali, Chiara Spadazzi, Federico La Manna, Alessandro De Vita, Nada Riva, Sebastiano Calpona, Marianna Ricci, Alberto Bongiovanni, Erica Gunelli,

Bone · 2014 · 39 citations · 39 references

Concepts

MedicineOncologyPharmacologyBone MetabolismCell SignalingMetastasisCancer Cell SignalingMalignant NeoplasmsMetastatic Breast CancerOncogenic Signaling PathwaysOsteoclast BiologyOsteoclast FunctionCancer Signaling PathwaysCo-culture ModelsColony-stimulating Factor 1 SignalingNf-κb SignalingOsteoclast InhibitionTumor-bone MicroenvironmentTumor-induced Osteoclastogenesis

References

39

New Colorimetric Cytotoxicity Assay for Anticancer-Drug Screening

Philip Skehan, Ritsa Storeng, Dominic A. Scudiero et al. · JNCI Journal of the National Cancer Institute · 1990 · 9.8K citations

Medicine, Oncology, Pharmacology +10

THE DISTRIBUTION OF SECONDARY GROWTHS IN CANCER OF THE BREAST.

Stephen A. Paget · The Lancet · 1889 · 5.1K citations

Medicine, Cancer Biology, Oncology +12

Feasibility of a High-Flux Anticancer Drug Screen Using a Diverse Panel of Cultured Human Tumor Cell Lines

Anne Monks, Dominic A. Scudiero, Philip Skehan et al. · JNCI Journal of the National Cancer Institute · 1991 · 3.3K citations

Medicine, Oncology, Pharmacology +11

Mechanisms of Bone Metastasis

G. David Roodman · New England Journal of Medicine · 2004 · 2.7K citations

Medicine, Oncology, Bone Metabolism +12

Denosumab Compared With Zoledronic Acid for the Treatment of Bone Metastases in Patients With Advanced Breast Cancer: A Randomized, Double-Blind Study

Alison Stopeck, Allan Lipton, Jean-Jacques Body et al. · Journal of Clinical Oncology · 2010 · 1.6K citations

Medicine, Pharmacology, Pharmacotherapy +17