Concepedia

Comparative toxicity of valproic acid and its metabolites in liver slices from adult rats, weanling rats and humans

Robyn L. Fisher, Jeffery T. Sanuik, H. Nau, A. Jay Gandolfi, Klaus Brendel

Toxicology in Vitro · 1994 · 19 citations · 25 references

DOI

Concepts

References

25

Valproic acid hepatic fatalities

Fritz E. Dreifuss, Nancy Santilli, D Langer et al. · Neurology · 1987 · 487 citations

, , +14

Valproate–Induced Hepatic Injury: Analyses of 23 Fatal Cases

Hyman J. Zimmerman, Kamal G. Ishak · Hepatology · 1982 · 394 citations · Full text

, , +17

A new instrument for the rapid preparation of tissue slices

Carlos L. Krumdieck, JoséErnesto dos Santos, Kang-Jey Ho · Analytical Biochemistry · 1980 · 290 citations

, , +7

The Hepatotoxicity of Valproic Acid and Its Metabolites in Rats. I. Toxicologic, Biochemical and Histopathologic Studies

J. W. Kesterson, Richard Granneman, Joseph M. Machinist · Hepatology · 1984 · 251 citations · Full text

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Cytochrome P-450—Catalyzed Formation of Δ<sup>4</sup>-VPA, a Toxic Metabolite of Valproic Acid

Allan E. Rettie, Albert W. Rettenmeier, William N. Howald et al. · Science · 1987 · 250 citations

, , +17