Concepedia

The CCR2/CCL2 Interaction Mediates the Transendothelial Recruitment of Intravascularly Delivered Neural Stem Cells to the Ischemic Brain

Robert H. Andres, Raymond Choi, Arjun V. Pendharkar, Xavier Gaeta, Nancy Wang, Jay K. Nathan, Joshua Y. Chua, Star W. Lee, Theo D. Palmer, Gary K. Steinberg,

Stroke · 2011 · 108 citations · 34 references

DOI

Abstract

The CCL2/CCR2 interaction is critical for transendothelial recruitment of intravascularly delivered NSC in response to ischemic injury. This finding could have significant implications in advancing minimally invasive intravascular therapeutics for regenerative medicine or cell-based drug delivery systems for central nervous system diseases.

References

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