Vox Sanguinis · 1977 · 29 citations · 10 references
MedicineHematologySeparation ProcessesStem Cell TransplantationTransfusion MedicinePlatelet ActivationPlatelet FunctionPlatelet PhysiologyPlatelet TransfusionRed Blood Cell TransfusionPlatelet CollectionPlatelet RecoveryPlatelet Separation
Plateletpheresis using the Haemonetics Model 30 cell separator results in a mean collection of 5.5 X 10(11) platelets. This product contains substantial numbers of erythrocytes and mononuclear cells which can be effectively removed by centrifugation but with a 23% loss of platelets as well. The mean decrement in donor's platelet count during the procedure, which is 78,000/mm3, is not commensurate with the number of platelets collected suggesting donor platelet mobilization. Platelets collected by this technic, when transfused into unselected recipients, give platelet increments comparable to platelets produced in the standard batch manner.
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Ronald A. Yankee, F. Carl Grumet, G. Nicholas Rogentine · New England Journal of Medicine · 1969 · 511 citations
Medicine, Hematology, Immunology +17
RH Herzig, GP Herzig, MI Bull et al. · Blood · 1975 · 142 citations · Full text
Medicine, Hematology, Immunology +13
Long-Term Platelet Support of Patients with Aplastic Anemia
F. Carl Grumet · Annals of Internal Medicine · 1970 · 106 citations