Protein evolution viewed through Escherichia coli Protein sequences: Introducing the notion of a structural segment of homology, the module

A general method applicable to the search for similarities in the amino acid sequence of two proteins

Saul B. Needleman, Christian D. Wunsch · Journal of Molecular Biology · 1970 · 11.4K citations

Amino Acid Sequence, Biochemistry, Structural Bioinformatics +14

Identification of common molecular subsequences

Temple F. Smith, Michael S. Waterman · Journal of Molecular Biology · 1981 · 10K citations

Sequence Motif, Functional Genomics, Natural Sciences +8

Whole-Genome Random Sequencing and Assembly of <i>Haemophilus influenzae</i> Rd

Robert Fleischmann, Mark D. Adams, Owen White et al. · Science · 1995 · 5.6K citations

Whole-genome Random Sequencing, Whole Chromosome, Genetics +12

Complete Genome Sequence of the Methanogenic Archaeon, <b> <i>Methanococcus jannaschii</i> </b>

Carol J. Bult, Owen White, Gary J. Olsen et al. · Science · 1996 · 2.1K citations

Biology, Microbial Systematics, Whole-genome Random Sequencing +15

Distinguishing Homologous from Analogous Proteins

Walter M. Fitch · Systematic Zoology · 1970 · 1.5K citations

Genetics, Molecular Biology, Molecular Genetics +21