New England Journal of Medicine · 1951 · 40 citations · 18 references
MedicineEndocrinologyInternal MedicineDiabetologyGeneral Internal MedicineHospital MedicineDiabetes ManagementDiabetes MellitusDiabetic KetoacidosisDiabetes Mellitus ManagementDiabetes MortalityDiabetic ComplicationsDiabetic Ketoacidosis ManagementModerate Acute IllnessSevere Acute Illness
A REVIEW of the results of treatment of diabetic coma on the Medical Service at the Massachusetts General Hospital in the pre-insulin era shows that the mortality rate was close to 100 per cent. In the period from January, 1942, to November, 1944, there was a mortality of 20 per cent in a series of 35 severe and moderately severe cases of diabetic acidosis. This drop in mortality in the twenty years following the discovery of insulin represents a tremendous improvement. However, such a mortality in any acute illness constitutes a serious challenge. At that time we had tended to . . .
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Edward C. Reifenstein, Fuller Albright, Shirley L. Wells · The Journal of Clinical Endocrinology & Metabolism · 1945 · 486 citations
Dana W. Atchley, Robert F. Loeb, Dickinson W. Richards et al. · Journal of Clinical Investigation · 1933 · 398 citations · Full text