Epigenetic Modulation of mGlu2 Receptors by Histone Deacetylase Inhibitors in the Treatment of Inflammatory Pain

The language of covalent histone modifications

Brian D. Strahl, C. David Allis · Nature · 2000 · 8.6K citations

Life Sciences, Biochemistry, Molecular Biology +12

Duration of Nuclear NF-κB Action Regulated by Reversible Acetylation

Lin‐Feng Chen, Wolfgang Fischle, Eric Verdin et al. · Science · 2001 · 1.2K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +14

Activation of mGlu2/3 receptors as a new approach to treat schizophrenia: a randomized Phase 2 clinical trial

Sandeep T. Patil, Lu Zhang, Ferenc Martényi et al. · Nature Medicine · 2007 · 1K citations

Medicine, Pharmacology, Psychiatry +12

Acetylation of RelA at discrete sites regulates distinct nuclear functions of NF‐κB

Lin Feng Chen, Yajun Mu, Warner C. Greene · The EMBO Journal · 2002 · 827 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +10

The p65 (RelA) Subunit of NF-κB Interacts with the Histone Deacetylase (HDAC) Corepressors HDAC1 and HDAC2 To Negatively Regulate Gene Expression

Brian P. Ashburner, Sandy D. Westerheide, Albert S. Baldwin · Molecular and Cellular Biology · 2001 · 732 citations · Full text

Life Sciences, Molecular Biology, Cell Signaling +14