Pax5 Promotes B Lymphopoiesis and Blocks T Cell Development by Repressing Notch1

Inducible Gene Targeting in Mice

Ralf Kühn, Frieder Schwenk, Michel Aguet et al. · Science · 1995 · 1.9K citations · Full text

Deficient T Cell Fate Specification in Mice with an Induced Inactivation of Notch1

Freddy Radtke, Anne E. Wilson, Gerlinde Stark et al. · Immunity · 1999 · 1.4K citations · Full text

Developmental Biology, Lymphocyte Development, Immunology +8

Commitment to the B-lymphoid lineage depends on the transcription factor Pax5

Stephen L. Nutt, Barry Heavey, Antonius Rolink et al. · Nature · 1999 · 1.2K citations

Lymphoid Neoplasia, Transcriptional Regulation, B-lymphoid Lineage +9

Notch1 Expression in Early Lymphopoiesis Influences B versus T Lineage Determination

John C. Pui, David Allman, Lanwei Xu et al. · Immunity · 1999 · 931 citations · Full text

A developmental pathway involving four phenotypically and functionally distinct subsets of CD3-CD4-CD8- triple-negative adult mouse thymocytes defined by CD44 and CD25 expression

Dale I. Godfrey, Jacqueline Kennedy, Toshio Suda et al. · The Journal of Immunology · 1993 · 835 citations · Full text