Extending the Vibrational Limits in Near-Infrared Fourier Transform Raman Spectroscopy

Abstract

Because of the throughput, multiplex, and calibration advantages of Fourier transform (FT) infrared spectroscopy, renewed interest has arisen in developing FT-Raman techniques for extended applications in the chemical, physical, and biophysical areas. The ability to use a single interferometer with the appropriate accessories for obtaining either infrared or Raman spectra adds further to the allure and potential of this new spectroscopic approach. As a result of the broad frequency range accessible to an interferometer, FT-Raman spectra can be collected with the use of a variety of laser excitation sources ranging from the visible (488 nm and 647.1 nm, for example) to near-infrared (1064 nm) wavelengths. Excitation at longer wavelengths often provides the significant advantage of yielding Raman spectra which are free from fluorescence effects.