Isolation of Toxoplasma from Cerebrospinal Fluid of a Living Infant in Holland

Abstract

SummaryThis is a report of a case of toxoplasmosis occurring in Holland in a six-week-old infant, in whom during life toxoplasma could be shown in the cerebrospinal fluid by smear and also isolated by mouse inoculation. The serum of the infant's mother showed a strongly positive neutralization reaction, which was carried out by Sabin's rabbit skin test. In cross-neutralization tests and cross-immunity experiments on rabbits, the Dutch strain appeared to be closely related, perhaps identical with an American one.