Biosynthesis of austin, a polyketide–terpenoid metabolite of Aspergillus ustus

Abstract

Incorporations of [1-13C]-, [2-13C]-, [1,2-13C2]- acetates and [Me-13C] methionine into austin, a metabolite of Aspergillus ustus, indicate its formation by a mixed polyketide-terpenoid biosynthetic pathway.