Haplotype-based case–control study between human apurinic/apyrimidinic endonuclease 1/redox effector factor-1 gene and cerebral infarction

On the advantage of haplotype analysis in the presence of multiple disease susceptibility alleles

Richard Morris, Norman Kaplan · Genetic Epidemiology · 2002 · 369 citations · Full text

Life Sciences, Biostatistics, Genetics +17

The redox and DNA-repair activities of Ref-1 are encoded by nonoverlapping domains.

Steven Xanthoudakis, Graham G. Miao, Tom Curran · Proceedings of the National Academy of Sciences · 1994 · 352 citations

Life Sciences, Biochemistry, Molecular Biology +15

A nonsynonymous SNP in PRKCH (protein kinase C η) increases the risk of cerebral infarction

Michiaki Kubo, Jun Hata, Toshiharu Ninomiya et al. · Nature Genetics · 2007 · 205 citations

Life Sciences, Molecular Biology, Molecular Genetics +12

Association between Polymorphisms in the DNA Repair Genes, <i>XRCC1, APE1</i>, and <i>XPD</i> and Acute Side Effects of Radiotherapy in Breast Cancer Patients

Jenny Chang‐Claude, Odilia Popanda, Xiang‐Lin Tan et al. · Clinical Cancer Research · 2005 · 172 citations · Full text

Medicine, Genetics, Oncology +17

Alterations in the expression of the apurinic/apyrimidinic endonuclease-1/redox factor-1 (APE/Ref-1) in human melanoma and identification of the therapeutic potential of resveratrol as an APE/Ref-1 inhibitor

Sun Yang, Kaikobad Irani, Susan Heffron et al. · Molecular Cancer Therapeutics · 2005 · 141 citations · Full text

Life Sciences, Molecular Biology, Oncology +16