Chemical Communications · 2012 · 68 citations · 12 references
PharmacyPharmaceuticsPharmacologyDrug DeliveryNanoparticle Drug DeliveryTargeted Drug DeliveryNanocarriers For TherapeuticsNanomaterials For Drug DeliveryNanomedicineNanoparticle Delivery SystemsNanoparticle FormulationsTargeted Drug Delivery SystemsDrug Delivery NanocarriersMultifunctional NanoparticlesNanocarriersNanoparticle DeliveryNanoparticle Drug TargetingNanoparticlesSelectivityTargeted Delivery
We demonstrate a new concept of carrier-free functionalized drug nanoparticles for targeted drug delivery. It exhibits significantly enhanced drug efficacy to folate receptor-positive cells with high selectivity and a high drug loading content up to more than 78%.
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Vascular permeability in a human tumor xenograft: molecular size dependence and cutoff size.
Marc Dellian, Dai Fukumura, Michael Leunig et al. · PubMed · 1995 · 1.7K citations
Medicine, Cancer Biology, Oncology +17