Inhibition of glutathione-dependent degradation of heme by chloroquine and amodiaquine as a possible basis for their antimalarial mode of action

Quantitative assessment of antimalarial activity in vitro by a semiautomated microdilution technique

R. E. Desjardins, Craig J. Canfield, J. David Haynes et al. · Antimicrobial Agents and Chemotherapy · 1979 · 2.5K citations · Full text

Medicine, Infectious Diseases, Pharmacology +17

Red Cell Metabolism: A Manual of Biochemical Methods.

Annals of Internal Medicine · 1971 · 2.3K citations

Life Sciences, Biochemistry, Physiology +11

Red Cell Metabolism. A Manual of Biochemical Methods.

Annals of Internal Medicine · 1975 · 1.8K citations

Life Sciences, Biochemistry, Physiology +10

Inhibition by chloroquine of a novel haem polymerase enzyme activity in malaria trophozoites

A.F.G. Slater, Anthony Cerami · Nature · 1992 · 651 citations

Life Sciences, Infectious Diseases, Molecular Biology +10

An iron-carboxylate bond links the heme units of malaria pigment.

A.F.G. Slater, William J. Swiggard, B. R. Orton et al. · Proceedings of the National Academy of Sciences · 1991 · 511 citations

Life Sciences, Biochemistry, Chemistry +15