Intact Doxil is taken up intracellularly and released doxorubicin sequesters in the lysosome: Evaluated by in vitro / in vivo live cell imaging

New Colorimetric Cytotoxicity Assay for Anticancer-Drug Screening

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Liposomal Doxorubicin Hcl, Metastatic Breast Cancer, Oncology +8

Prolonged circulation time and enhanced accumulation in malignant exudates of doxorubicin encapsulated in polyethylene-glycol coated liposomes.

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Engineering, Circulation Time, Pathology +22

Transmembrane ammonium sulfate gradients in liposomes produce efficient and stable entrapment of amphipathic weak bases

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Proteinlipid Interaction, Biochemistry, Natural Sciences +6

Preparation of unilamellar liposomes of intermediate size (0.1–0.2 μm) by a combination of reverse phase evaporation and extrusion through polycarbonate membranes

Francis C. Szoka, Fred C. Olson, Timothy D. Heath et al. · Biochimica et Biophysica Acta (BBA) - Biomembranes · 1980 · 474 citations

Lipid Preparation, Polycarbonate Membranes, Membrane Formation +3