Variation of the Radiobiological Oxygen Constant, <i>K</i> , with the Proliferative Activity of the Cells

Abstract

The value of K for mouse Ehrlich ascites cells depends on their phase of growth. Cells were grown either in vitro or in vivo but were irradiated and assayed in vitro. K was 1.7 times greater for cells in the exponential phase of growth than for those in plateau phase irrespective of the pre-irradiation growth conditions.