Concepedia

Disruption of ROCK1 gene attenuates cardiac dilation and improves contractile function in pathological cardiac hypertrophy

Jianjian Shi, Yi-Wei Zhang, Lelia J. Summers, Gerald W. Dorn, Lei Wei

Journal of Molecular and Cellular Cardiology · 2008 · 58 citations · 36 references

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36

Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension

Masayoshi Uehata, Toshimasa Ishizaki, Hiroyuki Satoh et al. · Nature · 1997 · 2.9K citations

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Pharmacological Properties of Y-27632, a Specific Inhibitor of Rho-Associated Kinases

Toshimasa Ishizaki, Masayoshi Uehata, Ichiro Tamechika et al. · Molecular Pharmacology · 2000 · 929 citations

, , +13

Transgenic Gαq overexpression induces cardiac contractile failure in mice

Drew D. D’Angelo, Yoshihito Sakata, John N. Lorenz et al. · Proceedings of the National Academy of Sciences · 1997 · 634 citations · Full text

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Enhanced Gαq signaling: A common pathway mediates cardiac hypertrophy and apoptotic heart failure

John W. Adams, Yoshihito Sakata, Michael Davis et al. · Proceedings of the National Academy of Sciences · 1998 · 535 citations

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Targeting the Receptor-G <sub>q</sub> Interface to Inhibit in Vivo Pressure Overload Myocardial Hypertrophy

Shahab A. Akhter, Louis M. Luttrell, Howard A. Rockman et al. · Science · 1998 · 456 citations

, , +17