Concepedia

Palladium(0)-Catalysed Arylations using Pyrrole and Indole 2-Boronic Acids

Christopher N. Johnson, Geoffrey Stemp, Neel K. Anand, Susanna C. Stephen, Timothy Gallagher

Synlett · 1998 · 70 citations · 0 references

Concepts

Natural SciencesChemistryMedicinal ChemistryCatalysisOrganic ChemistryCatalyst PreparationCatalyst SynthesisHeterocycle SynthesisHeterocyclic ChemistryOrganic SynthesisBorylation ReactionsHiyama CouplingIndole ChemistryIndole SynthesisPalladium CatalystsPalladium-catalyzed Cross-couplingPyrrole ChemistryPyrrole Synthesis

Abstract

A versatile synthesis of 2-arylpyrroles and 2-arylindoles is described based on the use of either N-(Boc) pyrrole-2-boronic acid or N-(Boc) indole-2-boronic acid as components for Suzuki coupling.