Nucleic Acids Research · 1989 · 19 citations · 3 references
Preparative IsolationCytogeneticsGeneticsDna AnalysisMolecular BiologyMolecular GeneticsYeastDna ComputingCloningExperimental ApplicationsGameteChromosomal RearrangementYeast Artificial ChromosomesChromatinGenetic EngineeringChromosome BiologyYac VectorsMedicineGenome Editing
Techniques for the cloning and analysis of very high molecular weight DNA in yeast artificial chromosomes (YACs) have recently been developed (1-3).The number of experimental applications for DNA cloned in YAC vectors has been somewhat limited by the lack of reliable
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