Secreted Protein Acidic and Rich in Cysteine (SPARC) Suppresses Angiogenesis by Down-Regulating the Expression of VEGF and MMP-7 in Gastric Cancer - Concepedia

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Secreted Protein Acidic and Rich in Cysteine (SPARC) Suppresses Angiogenesis by Down-Regulating the Expression of VEGF and MMP-7 in Gastric Cancer

DOI Full Paper Access

64

Citations

22

References

2012

Year

Junling Zhang, Guowei Chen, Yucun Liu, Peng‐Yuan Wang, Xin Wang, Yuan‐lian Wan, Jing Zhu, Hongqiao Gao, Jie Yin, Wei Wang,

Abstract

SPARC suppresses angiogenesis of gastric cancer by down-regulating the expression of VEGF and MMP-7.

References

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SPARC (BM-40, Osteonectin) Inhibits the Mitogenic Effect of Vascular Endothelial Growth Factor on Microvascular Endothelial Cells Christine Kupprion, Kouros Motamed, E. Helene Sage Journal of Biological Chemistry	1998	281
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A simple and fast densitometric method for the analysis of tyrosine hydroxylase immunoreactivity in the substantia nigra pars compacta and in the ventral tegmental area Léder Leal Xavier, Giordano Gübert Viola, Anete Curte Ferraz, Brain Research Protocols Fast Densitometric MethodBiochemistryTyrosine Hydroxylase ImmunoreactivityPharmacologyVentral Tegmental Area	2005	169
Overexpression of SPARC gene in human gastric carcinoma and its clinic–pathologic significance Wang Cs, Kwang‐Huei Lin, Shu‐Ling Chen, British Journal of Cancer	2004	118
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Relationship and prognostic significance of SPARC and VEGF protein expression in colon cancer Jianfang Liang, Hongkun Wang, Hong Xiao, Journal of Experimental & Clinical Cancer Research	2010	83
Secreted Protein Acidic and Rich in Cysteine (SPARC) Inhibits Integrin-Mediated Adhesion and Growth Factor-Dependent Survival Signaling in Ovarian Cancer Neveen Said, Ida Najwer, Kouros Motamed American Journal Of Pathology MedicineCell AdhesionProtein AcidicGynecologyIntegrin-mediated Adhesion	2007	83
MMP-7 (matrilysin) accelerated growth of human umbilical vein endothelial cells Nailin Huo, Yasushi Ichikawa, Masako Kamiyama, Cancer Letters AngiogenesisDevelopmental BiologyEndothelial DysfunctionVascular BiologyNeovascularization	2002	77

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