Physical, chemical and immunological stability of CHO-derived hepatitis B surface antigen (HBsAg) particles

Ultrasensitive Stain for Proteins in Polyacrylamide Gels Shows Regional Variation in Cerebrospinal Fluid Proteins

Carl R. Merril, David Goldman, S A Sedman et al. · Science · 1981 · 2.9K citations

Life Sciences, Biochemistry, Molecular Biology +17

Human hepatitis B vaccine from recombinant yeast

W. J. McAleer, Eugene B. Buynak, Robert Z. Maigetter et al. · Nature · 1984 · 735 citations

Life Sciences, Biotechnology, Infectious Diseases +14

Novel transmembrane topology of the hepatitis B virus envelope proteins.

Reinhild Prange, Rolf E. Streeck · The EMBO Journal · 1995 · 188 citations · Full text

Life Sciences, Infectious Diseases, Molecular Biology +14

Comparison between hepatitis B surface antigen (HBsAg) particles derived from mammalian cells (CHO) and yeast cells (Hansenula polymorpha): composition, structure and immunogenicity

Dvorah Diminsky, Reinhold Schirmbeck, Jörg Reimann et al. · Vaccine · 1997 · 129 citations

Life Sciences, Biochemistry, Molecular Biology +2

Antibody and cytotoxic T-cell responses to soluble hepatitis B virus (HBV) S antigen in mice: implication for the pathogenesis of HBV-induced hepatitis

Reinhold Schirmbeck, Karl Melber, Thomas Mertens et al. · Journal of Virology · 1994 · 91 citations · Full text

Life Sciences, Immunology, Infectious Diseases +17