Constitutive Expression of Multiple Growth Factor Genes by Melanoma Cells but Not Normal Melanocytes

Ulrich Rodeck, Karl Melber, R. Kath, +4

Journal of Investigative Dermatology

Developmental BiologyConstitutive ExpressionMelanomaCell ProliferationMelanoma Cells +6

Immunization with soluble hepatitis B virus surface protein elicits murine H-2 class I-restricted CD8+ cytotoxic T lymphocyte responses in vivo.

Reinhold Schirmbeck, Karl Melber, Andreas Kuhröber, +2

The Journal of Immunology

Adaptive Immune SystemImmunologyHepatitis BImmune RegulationAntigen Processing +15

Simultaneous expression of the S and L surface antigens of hepatitis B, and formation of mixed particles in the methylotrophic yeast, <i>Hansenula polymorpha</i>

Zbigniew A. Janowicz, Karl Melber, Armin Merckelbach, +4

Yeast

EngineeringHepatitis BSimultaneous ExpressionExpression SystemProtein Purification +19

Hepatitis B virus small surface antigen particles are processed in a novel endosomal pathway for major histocompatibility complex class I‐restricted epitope presentation

Reinhold Schirmbeck, Karl Melber, Jörg Reimann

European Journal of Immunology

Intranasal immunization with recombinant antigens associated with new cationic particles induces strong mucosal as well as systemic antibody and CTL responses

Arnaud Debin, Roger Kravtzoff, Jocelyn Vaz Santiago, +6

Vaccine

VaccinationMucosal VaccinationAutoimmune DiseaseAllergyIntranasal Immunization +11

Priming Th1 Immunity to Viral Core Particles Is Facilitated by Trace Amounts of RNA Bound to Its Arginine-Rich Domain

Petra Riedl, Detlef Stober, C Oehninger, +3

The Journal of Immunology

Viral ReplicationHumoral ResponseImmunologyMolecular BiologyImmunologic Mechanism +17

Exogenous hepatitis B surface antigen particles processed by dendritic cells or macrophages prime murine MHC class I-restricted cytotoxic T lymphocytes in vivo

W Böhm, Reinhold Schirmbeck, A Elbe, +6

The Journal of Immunology

Processing of exogenous heat-aggregated (denatured) and particulate (native) hepatitis B surface antigen for class I-restricted epitope presentation

Reinhold Schirmbeck, W Böhm, Karl Melber, +1

The Journal of Immunology

Antibody and cytotoxic T-cell responses to soluble hepatitis B virus (HBV) S antigen in mice: implication for the pathogenesis of HBV-induced hepatitis

Reinhold Schirmbeck, Karl Melber, Thomas Mertens, +1

Journal of Virology

Humoral ResponseImmunologyHepatitis BAntigen ProcessingHepatitis B Virus +17

A novel therapeutic hepatitis B vaccine induces cellular and humoral immune responses and breaks tolerance in hepatitis B virus (HBV) transgenic mice

Pascale Buchmann, Claudia J. Dembek, Larissa Kuklick, +7

Vaccine

VaccinationBreaks ToleranceVaccine DevelopmentViral HepatitisMedicine +10