[3H]Mesulergine, a selective ligand for serotonin-2 receptors

Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

Yung-Chi Cheng, William H. Prusoff · Biochemical Pharmacology · 1973 · 12.8K citations

Cent Inhibition, Inhibitory Activity, Biochemistry +8

Multiple Serotonin Receptors: Differential Binding of [3H]5-Hydroxytryptamine, [3H]Lysergic Acid Diethylamide and [3H]Spiroperidol

Stephen J. Peroutka, Solomon H. Snyder · Molecular Pharmacology · 1979 · 1.4K citations

[3H]Ketanserin (R 41 468), a selective 3H-ligand for serotonin2 receptor binding sites. Binding properties, brain distribution, and functional role.

J E Leysen, C. J. E. Niemegeers, Jan M. Van Nueten et al. · Molecular Pharmacology · 1982 · 1.1K citations

Molecular Pharmacology, Molecular Neuroscience, Neurophysiology +12

Receptor binding profile of R 41 468, A novel antagonist at 5-HT2 receptors

J.E. Leysen, F. Awouters, Ludo Kennis et al. · Life Sciences · 1981 · 844 citations

Signal Transduction, Biochemistry, R 41 +10

Long-Term Antidepressant Treatment Decreases Spiroperidol-Labeled Serotonin Receptor Binding

Stephen J. Peroutka, Solomon H. Snyder · Science · 1980 · 838 citations