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Life SciencesCell BiologyDermatologyApoptosisCarcinogenesisDna RepairApoptosis RegulationCell DeathCellular Radiation ResponseDna Damage-induced ApoptosisRadiation-induced Cell DeathUltraviolet Radiation BiologyApoptosis After IrradiationP53-mediated ApoptosisP53-mediated Cell DeathRadiation-induced ApoptosisUltraviolet Radiation Damage
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Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours
Lawrence A. Donehower, Michele Harvey, Betty L. Slagle et al. · Nature · 1992 · 4.7K citations
Participation of p53 protein in the cellular response to DNA damage.
Michael B. Kastan, Onyinye Onyekwere, D Sidransky et al. · PubMed · 1991 · 3.8K citations
p53 is required for radiation-induced apoptosis in mouse thymocytes
Scott W. Lowe, Earlene M. Schmitt, Sallie W. Smith et al. · Nature · 1993 · 2.9K citations
Medicine, Cell Biology, Oncology +14