Concepedia

Intraocular Toxicity and Pharmacokinetics of Candesartan in a Rabbit Model

Ji Eun Lee, Dae Won Lim, Hyun Jun Park, Jong Hun Shin, Seung Min Lee, Boo Sup Oum

Investigative Ophthalmology & Visual Science · 2011 · 12 citations · 25 references

DOI

Abstract

Intravitreal injection of 0.5 mg candesartan would be safe in the rabbit eyes. The half-life of candesartan was short in the vitreous, and modification of the delivery method would be required to extend the action duration for clinical applications.

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