Concepedia

Pirfenidone Nanoparticles Improve Corneal Wound Healing and Prevent Scarring Following Alkali Burn

Sushovan Chowdhury, Rajdeep Guha, Ruchit Trivedi, Uday B. Kompella, Aditya Konar, Sarbani Hazra

PLoS ONE · 2013 · 69 citations · 23 references

DOIFull text

Open access

Abstract

Pirfenidone decreases collagen synthesis and prevents myofibroblast formation. Pirfenidone nanoparticles improve corneal wound healing and prevent fibrosis. Pirfenidone nanoparticles are of potential value in treating corneal chemical burns and other corneal fibrotic diseases.

References

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