Hypersensitive response of malignant hyperthermia-susceptible skeletal muscle to inositol 1,4,5-trisphosphate induced release of calcium

Identification of a Mutation in Porcine Ryanodine Receptor Associated with Malignant Hyperthermia

Junichi Fujii, Kinya Otsu, Francesco Zorzato et al. · Science · 1991 · 1.5K citations

Agriculture, Animal Sciences, Veterinary Physiology +17

Inositol 1,4,5-trisphosphate: a possible chemical link in excitation-contraction coupling in muscle.

J Vergara, R Y Tsien, Michael DeLay · Proceedings of the National Academy of Sciences · 1985 · 326 citations · Full text

Life Sciences, Biochemistry, Physiology +17

Evidence for genetic heterogeneity in malignant hyperthermia susceptibility

Roy C. Levitt, N. Nouri, Anne Jedlicka et al. · Genomics · 1991 · 119 citations · Full text

Life Sciences, Genetics, Molecular Genetics +16

Pharmacologic differentiation between inositol-1,4,5-trisphosphate-induced Ca2+ release and Ca2+- or caffeine-induced Ca2+ release from intracellular membrane systems.

Philip Palade, Christine Dettbarn, Barbara H. Alderson et al. · Molecular Pharmacology · 1989 · 111 citations

Life Sciences, Neurobiology, Pharmacology +16

Myoplasmic free [Ca²⁺] during a malignant hyperthermia episode in swine

Jose R. Löapez, Paul D. Allen, Lorenzo Álamo et al. · Muscle & Nerve · 1988 · 96 citations

Medicine, Pharmacology, Veterinary Physiology +14