A component of green tea, (−)-epigallocatechin-3-gallate, promotes apoptosis in T24 human bladder cancer cells via modulation of the PI3K/Akt pathway and Bcl-2 family proteins

Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programed cell death

Zoltán N. Oltval, Curt Milliman, Stanley J. Korsmeyer · Cell · 1993 · 6K citations

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Prevention of Apoptosis by Bcl-2: Release of Cytochrome c from Mitochondria Blocked

Jie Yang, Xuesong Liu, Kapil N. Bhalla et al. · Science · 1997 · 4.9K citations

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Cleavage of Automodified Poly(ADP-ribose) Polymerase during Apoptosis

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Reduced Risk of Esophageal Cancer Associated With Green Tea Consumption

Yu‐Tang Gao, Joseph K. McLaughlin, W. J. Blot et al. · JNCI Journal of the National Cancer Institute · 1994 · 346 citations

Medicine, Biostatistics, Oncology +10

Epigallocatechin-3-gallate Inhibits Epidermal Growth Factor Receptor Signaling Pathway

Jerome F. Sah, Sivaprakasam Balasubramanian, Richard L. Eckert et al. · Journal of Biological Chemistry · 2004 · 235 citations · Full text

Life Sciences, Cell Biology, Pharmacology +17