On the biosynthesis of an inhibitor of the p53/MDM2 interaction

Oncoprotein MDM2 conceals the activation domain of tumour suppressor p53

Jonathan D. Oliner, Jennifer A. Pietenpol, Sam Thiagalingam et al. · Nature · 1993 · 1.5K citations

Medicine, Cancer Biology, Oncology +16

Isolation and Structure Elucidation of Chlorofusin, a Novel p53-MDM2 Antagonist from a <i>Fusarium</i> sp.

Sara J. Duncan, Sabine Grüschow, Dudley H. Williams et al. · Journal of the American Chemical Society · 2001 · 171 citations

Life Sciences, Medicinal Chemistry, Molecular Biology +17

Formation of water-solubleMonascus red pigments by biological and semi-synthetic processes

T. F. Lin, Kenichi Yakushijin, G. Büchi et al. · Journal of Industrial Microbiology & Biotechnology · 1992 · 152 citations

Life Sciences, Biochemistry, Microbiology +14

Overexpression of MDM2, due to enhanced translation, results in inactivation of wild-type p53 in Burkitt's lymphoma cells

Corinne Capoulade, Brigitte Bressac–de Paillerets, Isabelle Lefrère et al. · Oncogene · 1998 · 123 citations

Veterinary Medicine, Molecular Genetics, Oncology +14

A New Biosynthetic Pathway to Alkaloids in Plants: Acetogenic Isoquinolines

Gerhard Bringmann, Michael Wohlfarth, Heiko Rischer et al. · Angewandte Chemie International Edition · 2000 · 86 citations

Pharmacy, Botany, Plant Sciences +11