Concepedia

Identification of novel ROCK inhibitors with anti-migratory and anti-invasive activities

Ronil A. Patel, Yan Liu, Binglin Wang, Rongshi Li, Saı̈d Sebti

Oncogene · 2013 · 73 citations · 22 references

DOI

Concepts

References

22

Rho GTPases and their effector proteins

Anne L. Bishop, Alan Hall · Biochemical Journal · 2000 · 2K citations · Full text

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Genomic analysis of metastasis reveals an essential role for RhoC

Edwin Clark, Todd R. Golub, Eric S. Lander et al. · Nature · 2000 · 1.4K citations

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Rho GTPases are over-expressed in human tumors

Gerhard Fritz, Ingo Just, Bernd Kaina · International Journal of Cancer · 1999 · 662 citations

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An essential part for Rho–associated kinase in the transcellular invasion of tumor cells

Kazuyuki Itoh, Kiyoko Yoshioka, Hitoshi Akedo et al. · Nature Medicine · 1999 · 600 citations

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ROCK- and Myosin-Dependent Matrix Deformation Enables Protease-Independent Tumor-Cell Invasion In Vivo

Jeffrey Wyckoff, Sophie Pinner, Steve Gschmeissner et al. · Current Biology · 2006 · 435 citations · Full text

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