Nimesulide and renal impairment

Prostaglandin synthase 1 gene disruption in mice reduces arachidonic acid-induced inflammation and indomethacin-induced gastric ulceration

Robert Langenbach, Scott G. Morham, Howard F. Tiano et al. · Cell · 1995 · 1.1K citations · Full text

Life Sciences, Biochemistry, Pharmacology +16

Renal abnormalities and an altered inflammatory response in mice lacking cyclooxygenase II

Joseph Dinchuk, Bruce D. Car, Richard J. Focht et al. · Nature · 1995 · 968 citations

Medicine, Immunology, Nephrology +16

Localization of cyclooxygenase-1 and -2 in adult and fetal human kidney: implication for renal function

Martin Kömhoff, H.-J. Gröne, Thomas Klein et al. · American Journal of Physiology-Renal Physiology · 1997 · 362 citations

Life Sciences, Developmental Biology, Physiology +13

Renal and General Tolerability of Repeated Doses of Nimesulide in Normal Subjects

SJ Warrington, M. Ravic, ABS Dawnay · Drugs · 1993 · 20 citations

Pharmacy, Clinical Pharmacokinetics, Pharmacokinetics +8