Concepedia

Inhibition of secretory phospholipase A2. 2-Synthesis and structure–activity relationship studies of 4,5-dihydro-3-(4-tetradecyloxybenzyl)-1,2,4-4H-oxadiazol-5-one (PMS1062) derivatives specific for group II enzyme

Chang‐Zhi Dong, Azali Ahamada‐Himidi, Stéphanie Plocki, Darina Aoun, Mohamed Touaibia, Nadia Meddad-Bel Habich, Jack Huet, Catherine Redeuilh, Jean‐Edouard Ombetta, Jean‐Jacques Godfroid,

Bioorganic & Medicinal Chemistry · 2005 · 25 citations · 18 references

DOI

Concepts

References

18

Structures of Free and Inhibited Human Secretory Phospholipase A <sub>2</sub> from Inflammatory Exudate

David L. Scott, Steven P. White, Jeffrey L. Browning et al. · Science · 1991 · 252 citations

, , +16

X-ray structure of phospholipase A2 complexed with a substrate-derived inhibitor

Marjolein Thunnissen, Eiso AB, Kor H. Kalk et al. · Nature · 1990 · 245 citations

, , +12

Structure-based design of the first potent and selective inhibitor of human non-pancreatic secretory phospholipase A2

Richard W. Schevitz, Nicholas J. Bach, D. G. CARLSON et al. · Nature Structural & Molecular Biology · 1995 · 215 citations · Full text

, , +13

Roles of Trp31 in High Membrane Binding and Proinflammatory Activity of Human Group V Phospholipase A2

Sang Kyou Han, Kwang Pyo Kim, Rao S. Koduri et al. · Journal of Biological Chemistry · 1999 · 171 citations · Full text

, , +15

Pyrrolidine Inhibitors of Human Cytosolic Phospholipase A<sub>2</sub>

Kaoru Seno, Takayuki Okuno, Koichi Nishi et al. · Journal of Medicinal Chemistry · 2000 · 158 citations · Full text

, , +6