Systemic Macrophage Activation in Locally-induced Experimental Arthritis

Nitric oxide synthase structure and mechanism

Michael A. Marletta · Journal of Biological Chemistry · 1993 · 1.3K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +8

Discovery and analysis of inflammatory disease-related genes using cDNA microarrays

Renu A. Heller, Mark Schena, Andrew Chai et al. · Proceedings of the National Academy of Sciences · 1997 · 725 citations

Life Sciences, Immunology, Molecular Biology +17

Expression of the nitric oxide synthase gene in mouse macrophages activated for tumor cell killing. Molecular basis for the synergy between interferon-gamma and lipopolysaccharide.

Robert B. Lorsbach, William J. Murphy, Charles J. Lowenstein et al. · Journal of Biological Chemistry · 1993 · 621 citations · Full text

Life Sciences, Cell Biology, Immunology +13

IL-1 alpha beta blockade prevents cartilage and bone destruction in murine type II collagen-induced arthritis, whereas TNF-alpha blockade only ameliorates joint inflammation.

Leo A. B. Joosten, M.M. Helsen, Tore Saxne et al. · PubMed · 1999 · 442 citations

Medicine, Immunology, Pharmacology +17

IL-1αβ Blockade Prevents Cartilage and Bone Destruction in Murine Type II Collagen-Induced Arthritis, Whereas TNF-α Blockade Only Ameliorates Joint Inflammation

Leo A. B. Joosten, Monique M. Helsen, Tore Saxne et al. · The Journal of Immunology · 1999 · 397 citations · Full text

Medicine, Immunology, Pharmacology +17