A high content screening assay to predict human drug-induced liver injury during drug discovery

High concordance of drug-induced human hepatotoxicity with in vitro cytotoxicity measured in a novel cell-based model using high content screening

Peter J. O’Brien, William Irwin, Dolores Diaz et al. · Archives of Toxicology · 2006 · 606 citations

Hepatology, Health Sciences, Medicine +13

Cellular Imaging Predictions of Clinical Drug-Induced Liver Injury

Jinghai J. Xu, Peter Henstock, Margaret C. Dunn et al. · Toxicological Sciences · 2008 · 485 citations · Full text

Drug-Induced Liver Injury

Neil Kaplowitz · Clinical Infectious Diseases · 2004 · 393 citations

Pathology, Pharmacotherapy, Cirrhosis +18

Relationship between daily dose of oral medications and idiosyncratic drug-induced liver injury: Search for signals

Craig Lammert, Stefán Einarsson, Chandan Saha et al. · Hepatology · 2008 · 385 citations · Full text

Evaluation of the Characteristics of Safety Withdrawal of Prescription Drugs from Worldwide Pharmaceutical Markets-1960 to 1999

Fun Man Fung, Anna Thornton, Kathy Mybeck et al. · Drug Information Journal · 2001 · 375 citations

Drug Safety, Substance Abuse, Safety Withdrawal +8