Intramuscular Matrix-M-adjuvanted virosomal H5N1 vaccine induces high frequencies of multifunctional Th1 CD4+ cells and strong antibody responses in mice

Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins.

Timothy R. Mosmann, Holly Cherwinski, M W Bond et al. · The Journal of Immunology · 1986 · 7.5K citations

Adaptive Immune System, T-regulatory Cell, Cellular Immunology +19

Multifunctional TH1 cells define a correlate of vaccine-mediated protection against Leishmania major

Patricia A. Darrah, Dipti T. Patel, Paula Mello De Luca et al. · Nature Medicine · 2007 · 1.4K citations

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The role of serum haemagglutination-inhibiting antibody in protection against challenge infection with influenza A2 and B viruses

D. Hobson, R. L. Curry, A. S. Beare et al. · Epidemiology and Infection · 1972 · 1K citations · Full text

Vaccination, Vaccine Target, Humoral Response +12

Safety and Immunogenicity of an Inactivated Subvirion Influenza A (H5N1) Vaccine

John J. Treanor, James D. Campbell, Kenneth M. Zangwill et al. · New England Journal of Medicine · 2006 · 696 citations · Full text

Antigen sparing and cross-reactive immunity with an adjuvanted rH5N1 prototype pandemic influenza vaccine: a randomised controlled trial

Isabel Leroux‐Roels, Astrid Borkowski, Thomas Vanwolleghem et al. · The Lancet · 2007 · 500 citations

Vaccination, Cross-protection, Vaccine Development +9