Concepedia

Effects of Hypertonic Peritoneal Dialysis Solutions on Neutrophil Superoxide Production

Fang Zhou, Ferdinand J. Manahan, Alex Wai‐Yin Yu, Mohamed A. Rahman, Zeenat M. Nawab, Kenneth A. Fisher, Todd S. Ing

Artificial Organs · 1990 · 12 citations · 8 references

DOI

Concepts

Abstract

Superoxide produced by neutrophils plays an important role in the killing of bacterial pathogens. The effects of glucose-containing peritoneal dialysis solutions on superoxide production by canine and human neutrophils were studied. A significant decrement in superoxide generation was noted with the 2.27% and 3.86% glucose solutions. The results suggest that hypertonic peritoneal dialysis solutions curtail neutrophil superoxide generation.

References

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BM Babior · Blood · 1984 · 797 citations · Full text

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Biological Defense Mechanisms THE EFFECT OF BACTERIA AND SERUM ON SUPEROXIDE PRODUCTION BY GRANULOCYTES

John T. Curnutte, Bernard Babior · Journal of Clinical Investigation · 1974 · 310 citations · Full text

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Effects of the composition of peritoneal dialysis fluid on chemiluminescence, phagocytosis, and bactericidal activity in vitro

A K Duwe, Stephen I. Vas, Jill E. Weatherhead · Infection and Immunity · 1981 · 267 citations · Full text

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The effect of dialysate on peritoneal phagocyte oxidative metabolism

Nicholas Topley, Malcolm Davies, Gerald A. Coles et al. · Kidney International · 1988 · 171 citations · Full text

, , +12

Suppression of Neutrophil Superoxide Production by Conventional Peritoneal Dialysis Solution

Brian L. Ing, Dinesh Gupta, Zeenat M. Nawab et al. · The International Journal of Artificial Organs · 1988 · 65 citations

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