Serum Glutamic Oxalacetic Transaminase

Abstract

Transient and sometimes marked elevations of serum glutamic oxalacetic transaminase were found in each of seven young adult male volunteers by a standard colorimetric assay after oral administration of one or two courses of 4 gm of erythromycin estolate. These elevations were shown to be due not to the enzyme but to an unidentified, trypsin-stable substance related to the administration of the antibiotic.