Actinic Keratoses and the Incidence of Occult Squamous Cell Carcinoma: A Clinical?Histopathologic Correlation

Abstract

In this study, about 1 in 25 clinically diagnosed AK lesions identified by board-certified dermatologist investigator(s) were occult early-stage squamous cell carcinomas on histologic assessment, a fact surmised by the medical community that until now had not been well quantified. These findings should be considered when clinicians decide how to treat and manage AK patients.