Cyclooxygenase-2 expression and angiogenesis in squamous cell carcinoma of the skin and its precursors: a paired immunohistochemical study of 35 cases

Tamar Nijsten, Cécile Colpaert, P Vermeulen, Adrian L. Harris, E. Van Marck, Jo Lambert

British Journal of Dermatology · 2004 · 85 citations · 36 references

Abstract

Induction of COX-2 expression and angiogenesis are both early events in the development of SCC. In addition to ultraviolet light, hypoxia and COX-2 may be involved in skin tumour angiogenesis.

References

36