Journal of Parenteral and Enteral Nutrition · 2011 · 89 citations · 24 references
AgricultureNutritionNutritional SciencesClinical NutritionCritical Care MedicineNutritional Support In Critical CareCritical Care NutritionIntensive Care MedicineMedical Nutrition TherapyNutrition SupportNutritional SupportWeight ManagementCritical Care Nutrition TherapyFat Mass RedistributionImpaired Insulin SensitivityLean Body Mass LossNutrition In Critical IllnessObesity In Critical IllnessObesity Nutrition TherapyPatient Outcome Evaluation
This report compiles the conclusions and recommendations for nutrition therapy of the obese, critically ill patient derived by the group of experts participating in this workshop on obesity in critical care nutrition. The recommendations are based on consensus opinions of the group after review of the current literature. Obesity clearly adds to the complexity of nutrition therapy in the intensive care unit (ICU). Obesity alters the incidence and severity of comorbidities, tolerance of the prescribed regimen, and ultimately patient outcome through the course of hospitalization. Although the basic principles of critical care nutrition apply to the obese ICU patient, a high-protein, hypocaloric regimen should be provided to reduce the fat mass, improve insulin sensitivity, and preserve lean body mass. The ideal enteral formula should have a low nonprotein calorie to nitrogen ratio and have a variety of pharmaconutrient agents added to modulate immune responses and reduce inflammation.
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Pioglitazone, Vitamin E, or Placebo for Nonalcoholic Steatohepatitis
Arun J. Sanyal, Naga Chalasani, Kris V. Kowdley et al. · New England Journal of Medicine · 2010 · 3.3K citations · Full text
Stephen A. McClave, Robert G. Martindale, Vincent W. Vanek et al. · Journal of Parenteral and Enteral Nutrition · 2009 · 1.9K citations · Full text
Morbid Obesity in the Medical ICU
Ali El-Solh, Pawan Sikka, Erkan Bozkanat et al. · CHEST Journal · 2001 · 298 citations