Targeted insertion of the neomycin phosphotransferase gene into the tubulin gene cluster of Trypanosoma brucei

Transformation of yeast.

A. Hinnen, James Hicks, Gerald R. Fink · Proceedings of the National Academy of Sciences · 1978 · 2.2K citations · Full text

Engineering, Fungal Cell Biology, Genetics +18

Antigenic variation in trypanosoma brucei analyzed by electrophoretic separation of chromosome-sized DNA molecules

Lex H.T. Van der Ploeg, David C. Schwartz, Charles R. Cantor et al. · Cell · 1984 · 368 citations · Full text

Parasitic Protozoa, Trypanosoma Brucei, Genetics +11

Tubulin genes are tandemly linked and clustered in the genome of trypanosoma brucei

Linda S. Thomashow, Michael Milhausen, William J. Rutter et al. · Cell · 1983 · 259 citations

Bioinformatics, Parasitic Protozoa, Trypanosoma Brucei +9

Activation of trypanosome surface glycoprotein genes involves a duplication-transposition leading to an altered 3′ end

André Bernards, H.T. Lex, Ans van der Ploeg et al. · Cell · 1981 · 257 citations

Chromatin, Chromatin Structure, Altered 3′ +9

The promoter for a variant surface glycoprotein gene expression site in Trypanosoma brucei.

Joost C.B.M. Zomerdijk, Marc Ouellette, Anneloor L.M.A. ten Asbroek et al. · The EMBO Journal · 1990 · 212 citations · Full text

Parasitic Protozoa, Trypanosoma Brucei, Genetics +8